Publikationen / Publications
2022 2022 2021 2020 2019 2018 2017 2016
Aktories K (2022) Another surprise in receptor binding of C. difficile toxins. Innovation (Camb), 3, 100261
Abstract
Reuten R, Mayorca-Guiliani AE, Erler JT (2022) Matritecture: Mapping the extracellular matrix architecture during health and disease. Matrix Biol Plus, 14, 100102, 1-6
Abstract
2021 2022 2021 2020 2019 2018 2017 2016
Grossmann S, Mallmann RT, Klugbauer N (2021) Two-Pore Channels Regulate Expression of Various Receptors and Their Pathway-Related Proteins in Multiple Ways. Cells, 10, 1807, 1-13
Abstract
Kowarschik S, Schöllkopf J, Müller T, Tian S, Knerr J, Bakker H, Rein S, Dong M, Weber S, Grosse R, Schmidt G (2021) Yersinia pseudotuberculosis cytotoxic necrotizing factor interacts with glycosaminoglycans. FASEB J, 35, e21647, 1-16
Abstract
Li Y, Schön C, Chen CC, Yang Z, Liegl R, Murenu E, Schworm B, Klugbauer N, Grimm C, Wahl-Schott C, Michalakis S, Biel M (2021) TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration. Life Sci Alliance, 4, e202101047, 1-13
Abstract
Liang P, Schmitz C, Lace B, Ditengou FA, Su C, Schulze E, Knerr J, Grosse R, Keller J, Libourel C, Delaux PM, Ott T (2021) Formin-mediated bridging of cell wall, plasma membrane, and cytoskeleton in symbiotic infections of Medicago truncatula. Curr Biol, 31, 2712-19
Abstract
Müller T, Grossmann S, Mallmann RT, Rommel C, Hein L, Klugbauer N (2021) Two-pore channels affect EGF receptor signaling by receptor trafficking and expression. iScience, 24, 1-30
Abstract
Ng'ang'a PN, Siukstaite L, Lang AE, Bakker H, Römer W, Aktories K, Schmidt G (2021) Involvement of N-glycans in binding of Photorhabdus luminescens Tc toxin. Cell Microbiol, 23, e13326, 1-16
Abstract
Papatheodorou P, Kindig S, Badilla-Lobo A, Fischer S, Durgun E, Thuraisingam T, Witte A, Song S, Aktories K, Chaves-Olarte E, Rodríguez C, Barth H (2021) The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB. Front Microbiol, 12, 784856, 1-10
Abstract
Probst S, Sagar, Tosic J, Schwan C, Grün D, Arnold SJ (2021) Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation. Development, 48, dev193789, 1-15
Abstract
Safaralizade M, Fuderer R, Grosse R, Zhao B (2021) Measuring nuclear calcium and actin assembly in living cells. J Biochem, 169, 287-94
Abstract
Szczęśniak P, Henke T, Fröhlich S, Plessmann U, Urlaub H, Leng L, Bucala R, Grosse R, Meinhardt A, Klug J (2021) Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44. J Cell Sci, 134, 1-12
Abstract
Trefzer R, Elpeleg O, Gabrusskaya T, Stepensky P, Mor-Shaked H, Grosse R, Brandt DT (2021) Characterization of a L136P mutation in Formin-like 2 (FMNL2) from a patient with chronic inflammatory bowel disease. PLoS One, 16, e0252428, 1-17
Abstract
Ulferts S, Prajapati B, Grosse R, Vartiainen MK (2021) Emerging Properties and Functions of Actin and Actin Filaments Inside the Nucleus. Cold Spring Harb Perspect Biol, 13, 1-16
Abstract
Vannini E, Mori E, Tantillo E, Schmidt G, Caleo M, Costa M (2021) CTX-CNF1 Recombinant Protein Selectively Targets Glioma Cells In Vivo. Toxins (Basel), 13, 194, 1-11
Abstract
Weigang S, Fuchs J, Zimmer G, Schnepf D, Kern L, Beer J, Luxenburger H, Ankerhold J, Falcone V, Kemming J, Hofmann M, Thimme R, Neumann-Haefelin C, Ulferts S, Grosse R, Hornuss D, Tanriver Y, Rieg S, Wagner D, Huzly D, Schwemmle M, Panning M, Kochs G (2021) Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants. Nat Commun, 12, 6405, 1-12
Abstract
Zhao B, Grosse R (2021) Optogenetic Control of Myocardin-Related Transcription Factor A Subcellular Localization and Transcriptional Activity Steers Membrane Blebbing and Invasive Cancer Cell Motility. Adv Biol (Weinh), 5, 2000208, 1-10
Abstract
2020 2022 2021 2020 2019 2018 2017 2016
Aktories K (2020) Semaphorins or Frizzled -it is the receptor that direct the action of clostridial glucosylating toxins. Signal Transduct Target Ther, 5, 206, 1-2
Abstract
Antoni C, Quentin D, Lang AE, Aktories K, Gatsogiannis C, Raunser S (2020) Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state. PLoS Pathog, 16, e1008530, 1-19
Abstract
Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O'Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S (2020) TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity. Proc Natl Acad Sci U S A, 117, 18068-78
Abstract
Bouhaddou M, Memon D, Meyer B, White KM, Rezelj VV, Correa Marrero M, Polacco BJ, Melnyk JE, Ulferts S, Kaake RM, Batra J, Richards AL, Stevenson E, Gordon DE, Rojc A, Obernier K, Fabius JM, Soucheray M, Miorin L, Moreno E, Koh C, Tran QD, Hardy A, Robinot R, Vallet T, Nilsson-Payant BE, Hernandez-Armenta C, Dunham A, Weigang S, Knerr J, Modak M, Quintero D, Zhou Y, Dugourd A, Valdeolivas A, Patil T, Li Q, Hüttenhain R, Cakir M, Muralidharan M, Kim M, Jang G, Tutuncuoglu B, Hiatt J, Guo JZ, Xu J, Bouhaddou S, Mathy CJP, Gaulton A, Manners EJ, Félix E, Shi Y, Goff M, Lim JK, McBride T, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, De Wit E, Leach AR, Kortemme T, Shoichet B, Ott M, Saez-Rodriguez J, tenOever BR, Mullins RD, Fischer ER, Kochs G, Grosse R, García-Sastre A, Vignuzzi M, Johnson JR, Shokat KM, Swaney DL, Beltrao P, Krogan NJ (2020) The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell, 182, 685-712
Abstract
Fischer S, Ückert AK, Landenberger M, Papatheodorou P, Hoffmann-Richter C, Mittler AK, Ziener U, Hägele M, Schwan C, Müller M, Kleger A, Benz R, Popoff MR, Aktories K, Barth H (2020) Human Peptide α-defensin-1 Interferes With Clostridioides Difficile Toxins TcdA, TcdB, and CDT. FASEB J, 34, 6244-61
Abstract
Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR 3rd, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH Jr, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D; QCRG Structural Biology Consortium, Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL; Zoonomia Consortium, Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, García-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ (2020) Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science, 370, eabe9403, 1-25
Abstract
Korbmacher M, Fischer S, Landenberger M, Papatheodorou P, Aktories K, Barth H (2020) Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT. Front Pharmacol, 11, 1204, 1-10
Abstract
Krippner S, Winkelmeier J, Knerr J, Brandt DT, Virant D, Schwan C, Endesfelder U, Grosse R (2020) Postmitotic expansion of cell nuclei requires nuclear actin filament bundling by α-actinin 4. EMBO Rep, 21, e50758, 1-11
Abstract
Lacinova L, Mallmann RT, Jurkovičová-Tarabová B, Klugbauer N (2020) Modulation of voltage-gated CaV2.2 Ca2+ channels by newly identified interaction partners. Channels (Austin), 14, 380-92
Abstract
Mallmann RT, Klugbauer N (2020) Genetic Inactivation of Two-Pore Channel 1 Impairs Spatial Learning and Memory. Behav Genet, 50, 401-10
Abstract
Okuno T, Li WY, Hatano Y, Takasu A, Sakamoto Y, Yamamoto M, Ikeda Z, Shindo T, Plessner M, Morita K, Matsumoto K, Yamagata K, Grosse R, Miyamoto K (2020) Zygotic Nuclear F-Actin Safeguards Embryonic Development. Cell Rep, 31, 107824, 1-23
Abstract
Ost GS, Wirth C, Bogdanović X, Kao WC, Schorch B, Aktories PJK, Papatheodorou P, Schwan C, Schlosser A, Jank T, Hunte C, Aktories K (2020) Inverse Control of Rab Proteins by Yersinia ADP-ribosyltransferase and Glycosyltransferase Related to Clostridial Glucosylating Toxins. Sci Adv, 6, eaaz2094, 1-12
Abstract
Richter L, Oberländer V, Schmidt G (2020) RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A. Sci Rep, 10, 12532, 1-11
Abstract
Schiavon, C. R., Zhang, T., Zhao, B., Moore, A. S., Wales, P., Andrade, L. R., Wu, M., Sung, T. C., Dayn, Y., Feng, J. W., Quintero, O. A., Shadel, G. S., Grosse, R., & Manor, U (2020) Actin chromobody imaging reveals sub-organellar actin dynamics. Nature methods, 17, 917–21
Abstract
Schwan C, Grosse R (2020) A tight grip on differentiation: Nuclear constriction by microtubules regulates hematopoietic stem cells. EMBO J, e107086, 1-3
Abstract
Simpson M, Frisbee A, Kumar P, Schwan C, Aktories K, Petri WA (2020) Clostridioides difficile binary toxin (CDT) is recognized by the TLR2/6 heterodimer to induce an NF-κB response. J Infect Dis, 225, 1296-300
Abstract
Taskinen ME, Närvä E, Conway JRW, Hinojosa LS, Lilla S, Mai A, De Franceschi N, Elo LL, Grosse R, Zanivan S, Norman JC, Ivaska J (2020) MASTL Promotes Cell Contractility and Motility Through Kinase-Independent Signaling. J Cell Biol, 219, e201906204, 1-23
Abstract
Yamazaki S, Gerhold C, Yamamoto K, Ueno Y, Grosse R, Miyamoto K, Harata M (2020) The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin. Cells, 9, 758, 1-14
Abstract
2019 2022 2021 2020 2019 2018 2017 2016
Abdellatif MEA, Hipp L, Plessner M, Walther P, Knöll B (2019) Indirect visualization of endogenous nuclear actin by correlative light and electron microscopy (CLEM) using an actin-directed chromobody. Histochem Cell Biol, 152, 133-43
Abstract
Aktories K, Gierschik P, Heringdorf DMZ, Schmidt M, Schultz G, Wieland T (2019) cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology-tribute to Karl H. Jakobs. Naunyn Schmiedebergs Arch Pharmacol, 392, 887-911
Abstract
Almonacid M, Al Jord A, El-Hayek S, Othmani A, Coulpier F, Lemoine S, Miyamoto K, Grosse R, Klein C, Piolot T, Mailly P, Voituriez R, Genovesio A, Verlhac MH (2019) Active Fluctuations of the Nuclear Envelope Shape the Transcriptional Dynamics in Oocytes. Dev Cell, 51, 145-57
Abstract
Bogdanović X, Schneider S, Levanova N, Wirth C, Trillhaase C, Steinemann M, Hunte C, Aktories K, Jank T (2019) A cysteine protease-like domain enhances the cytotoxic effects of the Photorhabdus asymbiotica toxin PaTox. J Biol Chem, 294, 1035-44
Abstract
Brander S, Jank T, Hugel T (2019) AFM Imaging Suggests Receptor-Free Penetration of Lipid Bilayers by Toxins. Langmuir, 35, 365-71
Abstract
Caridi CP, Plessner M, Grosse R, Chiolo I (2019) Nuclear actin filaments in DNA repair dynamics. Nat Cell Biol, 21, 1068-77
Abstract
Chleilat E, Mallmann R, Spanagel R, Klugbauer N, Krieglstein K, Roussa E (2019) Spatiotemporal Role of Transforming Growth Factor Beta 2 in Developing and Mature Mouse Hindbrain Serotonergic Neurons. Front Cell Neurosci, 13, 427, 1-19
Abstract
Ebner JK, König GM, Kostenis E, Siegert P, Aktories K, Orth JH (2019) Activation of Gq signaling by Pasteurella multocida toxin inhibits the osteoblastogenic-like actions of Activin A in C2C12 myoblasts, a cell model of fibrodysplasia ossificans progressiva. Bone, 127, 592-601
Abstract
Levanova N, Mattheis C, Carson D, To KN, Jank T, Frankel G, Aktories K, Schroeder GN (2019) The Legionella effector LtpM is a new type of phosphoinositide-activated glucosyltransferase. J Biol Chem, 294, 2862-79
Abstract
Levanova N, Steinemann M, Böhmer KE, Schneider S, Belyi Y, Schlosser A, Aktories K, Jank T (2019) Characterization of the glucosyltransferase activity of Legionella pneumophila effector SetA. Naunyn Schmiedebergs Arch Pharmacol, 392, 69-79
Abstract
López-Ureña D, Orozco-Aguilar J, Chaves-Madrigal Y, Ramírez-Mata A, Villalobos-Jimenez A, Ost S, Quesada-Gómez C, Rodríguez C, Papatheodorou P, Chaves-Olarte E (2019) Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors. Toxins (Basel). 11, 384, 1-15
Abstract
Mallmann RT, Moravcikova L, Ondacova K, Lacinova L, Klugbauer N (2019) Grina/TMBIM3 modulates voltage-gated Cav2.2 Ca2+ channels in a G-protein-like manner. Cell Calcium, 80, 71-8
Abstract
Mallmann R, Ondacova K, Moravcikova L, Jurkovicova-Tarabova B, Pavlovicova M, Moravcik R, Lichvarova L, Kominkova V, Klugbauer N, Lacinova L (2019) Four novel interaction partners demonstrate diverse modulatory effects on voltage-gated CaV2.2 Ca2+ channels. Pflugers Arch, 471, 861-74
Abstract
Müller CS, Bildl W, Klugbauer N, Haupt A, Fakler B, Schulte U (2019) High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis. J Vis Exp, 152, e60096, 1-10
Abstract
Ng Ang A PN, Ebner JK, Plessner M, Aktories K, Schmidt G (2019) Engineering Photorhabdus luminescens toxin complex (PTC) into a recombinant injection nanomachine. Life Sci Alliance, 2, e20190048, 1-12
Abstract
Ost GS, Ng'ang'a PN, Lang A, Aktories K (2019) Photorhabdus luminescens Tc toxin is inhibited by the protease inhibitor MG132 and activated by protease cleavage resulting in increased binding to target cells. Cell Microbiol, 21, e12978, 1-12
Abstract
Papatheodorou P, Song S, López-Ureña D, Witte A, Marques F, Ost GS, Schorch B, Chaves-Olarte E, Aktories K (2019) Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway. FASEB J, 33, 4883-92
Abstract
Plessner M, Grosse R (2019) Dynamizing nuclear actin filaments. Curr Opin Cell Biol, 56, 1-6
Abstract
Plessner M, Knerr J, Grosse R (2019) Centrosomal Actin Assembly Is Required for Proper Mitotic Spindle Formation and Chromosome Congression. iScience, 15, 274-81
Abstract
Reinartz S, Lieber S, Pesek J, Brandt DT, Asafova A, Finkernagel F, Watzer B, Nockher WA, Nist A, Stiewe T, Jansen JM, Wagner U, Konzer A, Graumann J, Grosse R, Worzfeld T, Müller-Brüsselbach S, Müller R (2019) Cell type-selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment. Mol Oncol, 13, 185-201
Abstract
Schnell L, Felix I, Müller B, Sadi M, von Bank F, Papatheodorou P, Popoff MR, Aktories K, Waltenberger E, Benz R, Weichbrodt C, Fauler M, Frick M, Barth H (2019) Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication. FASEB J, 33, 5755-71
Abstract
Stroukov W, Rösch A, Schwan C, Jeney A, Römer W, Thuenauer R (2019) Synchronizing Protein Traffic to the Primary Cilium. Front Genet, 10, 163, 1-10
Abstract
Tsopoulidis N, Kaw S, Laketa V, Kutscheidt S, Baarlink C, Stolp B, Grosse R, Fackler OT (2019) T cell receptor-triggered nuclear actin network formation drives CD4+ T cell effector functions. Sci Immunol, 4, eaav1987, 1-11
Abstract
Wang Y, Sherrard A, Zhao B, Melak M, Trautwein J, Kleinschnitz EM, Tsopoulidis N, Fackler OT, Schwan C, Grosse R (2019) GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics. Nat Commun, 10, 5271, 1-9
Abstract
2018 2022 2021 2020 2019 2018 2017 2016
Aktories K, Papatheodorou P, Schwan C (2018) Binary Clostridium difficile toxin (CDT) - A virulence factor disturbing the cytoskeleton. Anaerobe, 53, 21-9
Abstract
Brink T, Leiss V, Siegert P, Jehle D, Ebner JK, Schwan C, Shymanets A, Wiese S, Nürnberg B, Hensel M, Aktories K, Orth JHC (2018) Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins. PLoS Pathog, 14, e1007248, 1-23
Abstract
Haun F, Neumann S, Peintner L, Wieland K, Habicht J, Schwan C, Østevold K, Koczorowska MM, Biniossek M, Kist M, Busch H, Boerries M, Davis RJ, Maurer U, Schilling O, Aktories K, Borner C (2018) Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin. Nat Commun, 9, 3524, 1-14
Abstract
Heni H, Ebner JK, Schmidt G, Aktories K, Orth JHC (2018) Involvement of Osteocytes in the Action of Pasteurella multocida Toxin. Toxins (Basel), 10, 328, 1-15
Abstract
Normann C, Frase S, Haug V, von Wolff G, Clark K, Münzer P, Dorner A, Scholliers J, Horn M, Vo Van T, Seifert G, Serchov T, Biber K, Nissen C, Klugbauer N, Bischofberger J (2018) Antidepressants Rescue Stress-Induced Disruption of Synaptic Plasticity via Serotonin Transporter-Independent Inhibition of L-Type Calcium Channels. Biol Psychiatry, 84, 55-64
Abstract
Papatheodorou P, Barth H, Minton N, Aktories K (2018) Cellular Uptake and Mode-of-Action of Clostridium difficile Toxins. Adv Exp Med Biol, 1050, 77-96
Abstract
Schmidt G (2018) Methods to Study Rho GTPases Using Bacterial Toxins. Methods Mol Biol, 1821, 141-54
Abstract
Schorch B, Heni H, Zahaf NI, Brummer T, Mione M, Schmidt G, Papatheodorou P, Aktories K (2018) Targeting oncogenic Ras by the Clostridium perfringens toxin TpeL. Oncotarget, 9, 16489-500
Abstract
Steinemann M, Schlosser A, Jank T, Aktories K (2018) The chaperonin TRiC/CCT is essential for the action of bacterial glycosylating protein toxins like Clostridium difficile toxins A and B. Proc Natl Acad Sci U S A, 115, 9580-5
Abstract
2017 2022 2021 2020 2019 2018 2017 2016
Aktories K, Schwan C, Lang AE (2017) ADP-Ribosylation and Cross-Linking of Actin by Bacterial Protein Toxins. Handb Exp Pharmacol, 235, 179-206
Abstract
Aktories K, Schwan C, Jank T (2017) Clostridium difficile Toxin Biology. Annu Rev Microbiol, 71, 281-307
Abstract
Baarlink C, Plessner M, Sherrard A, Morita K, Misu S, Virant D, Kleinschnitz EM, Harniman R, Alibhai D, Baumeister S, Miyamoto K, Endesfelder U, Kaidi A, Grosse R (2017) A transient pool of nuclear F-actin at mitotic exit controls chromatin organization. Nat Cell Biol, 19, 1389-99
Abstract
Carle S, Brink T, Orth JH, Aktories K, Barth H (2017) Auranofin Inhibits the Enzyme Activity of Pasteurella multocida Toxin PMT in Human Cells and Protects Cells from Intoxication. Toxins (Basel), 9, 32, 1-8
Abstract
Castonguay J, Orth JHC, Müller T, Sleman F, Grimm C, Wahl-Schott C, Biel M, Mallmann RT, Bildl W, Schulte U, Klugbauer N (2017) The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes. Sci Rep, 7, 10038, 1-15
Abstract
Czulkies BA, Mastroianni J, Lutz L, Lang S, Schwan C, Schmidt G, Lassmann S, Zeiser R, Aktories K, Papatheodorou P (2017) Loss of LSR affects epithelial barrier integrity and tumor xenograft growth of CaCo-2 cells. Oncotarget, 8, 37009-22
Abstract
Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H (2017) Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells. Sci Rep, 7, 2724, 1-16
Abstract
Jank T, Belyi Y, Wirth C, Rospert S, Hu Z, Dengjel J, Tzivelekidis T, Andersen GR, Hunte C, Schlosser A, Aktories K (2017) Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. J Biol Chem, 292, 16014-23
Abstract
Harterink M, da Silva ME, Will L, Turan J, Ibrahim A, Lang AE, van Battum EY, Pasterkamp RJ, Kapitein LC, Kudryashov D, Barres BA, Hoogenraad CC, Zuchero JB (2017) DeActs: genetically encoded tools for perturbing the actin cytoskeleton in single cells. Nat Methods, 14, 479-82
Abstract
Hinojosa LS, Holst M, Baarlink C, Grosse R (2017) MRTF transcription and Ezrin-dependent plasma membrane blebbing are required for entotic invasion. J Cell Biol, 216, 3087-95
Abstract
Klugbauer N (2017) New clues on Sidt2 being a cation conducting protein in lysosomal membranes. FEBS Lett, 591, 3-4
Abstract
Lang AE, Qu Z, Schwan C, Silvan U, Unger A, Schoenenberger CA, Aktories K, Mannherz HG (2017) Actin ADP-ribosylation at Threonine148 by Photorhabdus luminescens toxin TccC3 induces aggregation of intracellular F-actin. Cell Microbiol, 19, 1-14
Abstract
Lang S, Busch H, Boerries M, Brummer T, Timme S, Lassmann S, Aktories K, Schmidt G (2017) Specific role of RhoC in tumor invasion and metastasis. Oncotarget, 8, 87364-78
Abstract
Melak M, Plessner M, Grosse R (2017) Actin visualization at a glance. J Cell Sci, 130, 525-30
Abstract
Østevold K, Meléndez AV, Lehmann F, Schmidt G, Aktories K, Schwan C (2017) Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells. Oncotarget, 8, 76686-98
Abstract
Papatheodorou P, Aktories K (2017) Receptor-Binding and Uptake of Binary Actin-ADP-Ribosylating Toxins. Curr Top Microbiol Immunol, 406, 119-33
Abstract
Reppin F, Cochet S, El Nemer W, Fritz G, Schmidt G (2017) High Affinity Binding of Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1) to Lu/BCAM Adhesion Glycoprotein. Toxins (Basel), 10, 3, 1-14
Abstract
Schuster M, Schnell L, Feigl P, Birkhofer C, Mohr K, Roeder M, Carle S, Langer S, Tippel F, Buchner J, Fischer G, Hausch F, Frick M, Schwan C, Aktories K, Schiene-Fischer C, Barth H (2017) The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells. Sci Rep, 7, 613, 1-14
Abstract
Schwan C, Aktories K (2017) Formation of Nanotube-Like Protrusions, Regulation of Septin Organization and Re-guidance of Vesicle Traffic by Depolymerization of the Actin Cytoskeleton Induced by Binary Bacterial Protein Toxins. Curr Top Microbiol Immunol, 399, 35-51
Abstract
Sheets J, Aktories K (2017) Insecticidal Toxin Complexes from Photorhabdus luminescens. Curr Top Microbiol Immunol, 402, 3-23
Abstract
Zahaf NI, Lang AE, Kaiser L, Fichter CD, Lassmann S, McCluskey A, Augspach A, Aktories K, Schmidt G (2017) Targeted delivery of an ADP-ribosylating bacterial toxin into cancer cells. Sci Rep, 7, 41252, 1-10
Abstract
Zahaf NI, Schmidt G (2017) Bacterial Toxins for Cancer Therapy. Toxins (Basel), 9, 236, 1-11
Abstract
07. Juni 2022